Anti-Shank1 Antibody 75-064 from Antibodies Inc.

Product Specs
ItemAnti-Shank1 Antibody
CompanyAntibodies Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number75-064
Antibody TypePrimary Antibody
ClonalityMonoclonal
ReactivityHuman, Mouse, and Rat
Regulatory StatusThese antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans
FormatLiquid, Purified by Protein A chromatography
ApplicationsIHC, ICC, WB
CloneN22/21
Gene NameShank1
HostMouse
Quantity100 µL
Molecular Weight190-220 kDa (alternative splice variants)
TargetShank1
IsotypeIgG1
Conjugate/TagUnconjugated
Brand/TrademarkNeuroMab
ImmunogenFusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1 (accession number Q9WV48) produced recombinantly in E. Coli
ValidationEach new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band
NCBI Gene AliasesShank1a, Spank1, Sstrip

P.O. Box 1560

Davis, CA 95617-1560

United States

Phone: (800) 824-8540

Email: orders@antibodiesinc.com

(2) Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapsesThe European journal of neuroscienceJanuary 1, 2016MacGillavry HD, Kerr JM, Kassner J, Frost NA, Blanpied TA.

(3) Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levelsThe Journal of cell biologyNovember 9, 2015Schreiber J, Végh MJ, Dawitz J, Kroon T, Loos M, Labonté D, Li KW, Van Nierop P, Van Diepen MT, De Zeeuw CI, et al.

(5) SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic propertiesNatureNovember 7, 2013Han K, Holder JL Jr, Schaaf CP, Lu H, Chen H, Kang H, Tang J, Wu Z, Hao S, Cheung SW, et al.

(6) Regulation of synapse composition by protein acetylation: the role of acetylated cortactinJournal of cell scienceJanuary 1, 2013Catarino T, Ribeiro L, Santos SD, Carvalho AL.

(7) Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapsesThe Journal of biological chemistryOctober 7, 2011Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Böckers TM, et al.

Anti-Shank1 Antibody from Antibodies Inc.